Arenavirus-Mediated Liver Pathology: Acute Lymphocytic Choriomeningitis Virus Infection of Rhesus Macaques Is Characterized by High-Level Interleukin-6 Expression and Hepatocyte Proliferation

Lymphocytic choriomeningitis virus (LCMV) and Lassa virus can cause hemorrhagic fever and liver disease in primates. The WE strain of LCMV (LCMV-WE) causes a fatal Lassa fever-like disease in rhesus macaques and provides a model for arenavirus pathogenesis in humans. LCMV-WE delivered intravenously...

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Hlavní autoři: Lukashevich, Igor S., Tikhonov, Ilia, Rodas, Juan D., Zapata, Juan C., Yang, Yida, Djavani, Mahmoud, Salvato, Maria S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC140927/
https://ncbi.nlm.nih.gov/pubmed/12525606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.3.1727-1737.2003
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