Bmp in Podocytes Is Essential for Normal Glomerular Capillary Formation

Bone morphogenetic protein (BMP) 4 exerts multiple biological effects on kidney and ureter development. To examine the role of BMP4 in glomerular morphogenesis, we generated transgenic mice with altered BMP4 function in podocytes by conferring tissue-specificity with the nephrin (Nphs1) promoter. At...

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Bibliographic Details
Main Authors: Ueda, Hiroyuki, Miyazaki, Yoichi, Matsusaka, Taiji, Utsunomiya, Yasunori, Kawamura, Tetsuya, Hosoya, Tatsuo, Ichikawa, Iekuni
Format: Artigo
Language:Inglês
Published: American Society of Nephrology 2008
Subjects:
Basic Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390961/
https://ncbi.nlm.nih.gov/pubmed/18272846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2006090983
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