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Bmp in Podocytes Is Essential for Normal Glomerular Capillary Formation

Bone morphogenetic protein (BMP) 4 exerts multiple biological effects on kidney and ureter development. To examine the role of BMP4 in glomerular morphogenesis, we generated transgenic mice with altered BMP4 function in podocytes by conferring tissue-specificity with the nephrin (Nphs1) promoter. At...

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Detalhes bibliográficos
Main Authors: Ueda, Hiroyuki, Miyazaki, Yoichi, Matsusaka, Taiji, Utsunomiya, Yasunori, Kawamura, Tetsuya, Hosoya, Tatsuo, Ichikawa, Iekuni
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390961/
https://ncbi.nlm.nih.gov/pubmed/18272846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2006090983
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