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TGFβ primes breast tumors for lung metastasis seeding through angiopoietin-like 4
Cells released from primary tumors seed metastases to specific organs by a non-random process, implying the involvement of biologically selective mechanisms. Based on clinical, functional and molecular evidence, we show that the cytokine TGFβ in the breast tumor microenvironment primes cancer cells...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2390892/ https://ncbi.nlm.nih.gov/pubmed/18394990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.01.046 |
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