Reduction of digoxin to 20R-dihydrodigoxin by cultures of Eubacterium lentum.
The anaerobic bacterium Eubacterium lentum, a common constituent of the intestinal microflora, inactivates digoxin by reducing the unsaturated lactone ring. Reduction of the cardiac glycoside by growing cultures of E. lentum ATCC 25559 proceeded in a stereospecific manner, with the 20R-dihydrodigoxi...
שמור ב:
| הוצא לאור ב: | Appl Environ Microbiol |
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| Principais autores: | , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Microbiology (ASM)
1986
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC239061/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3729400/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.51.6.1300-1303.1986 |
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