Legionella pneumophila infection induces programmed cell death, caspase activation, and release of high-mobility group box 1 protein in A549 alveolar epithelial cells: inhibition by methyl prednisolone

BACKGROUND: Legionella pneumophila pneumonia often exacerbates acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Apoptosis of alveolar epithelial cells is considered to play an important role in the pathogenesis of ALI and ARDS. In this study, we investigated the precise mechan...

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Detalhes bibliográficos
Main Authors: Furugen, Makoto, Higa, Futoshi, Hibiya, Kenji, Teruya, Hiromitsu, Akamine, Morikazu, Haranaga, Shusaku, Yara, Satomi, Koide, Michio, Tateyama, Masao, Mori, Naoki, Fujita, Jiro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390540/
https://ncbi.nlm.nih.gov/pubmed/18447956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-9-39
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