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Hematopoietic cell survival signals are elicited through non–tyrosine-containing sequences in the membrane-proximal region of the erythropoietin receptor (EPOR) by a Stat5-dependent pathway

OBJECTIVE: Erythropoietin is essential for red blood cell development in vivo and is also an important therapeutic agent to treat anemia resulting from kidney failure or bone marrow suppression. The erythropoietin receptor (EPOR) elicits both positive and negative regulatory signaling pathways, prim...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yoon, Donghoon, Watowich, Stephanie S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2388246/
https://ncbi.nlm.nih.gov/pubmed/14662339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2003.08.009
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