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Role of the Stat4 N Domain in Receptor Proximal Tyrosine Phosphorylation

Stat4 is activated by the cytokines interleukin 12 and alpha interferon (IFN-α) and plays a significant role in directing development of naïve CD4(+) T cells to the Th1 phenotype. Signal transducers and activators of transcription (STAT) proteins undergo phosphorylation on a conserved tyrosine resid...

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Detalhes bibliográficos
Main Authors: Murphy, Theresa L., Geissal, Erik D., Farrar, J. David, Murphy, Kenneth M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC86263/
https://ncbi.nlm.nih.gov/pubmed/10982828
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