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Hematopoietic cell survival signals are elicited through non–tyrosine-containing sequences in the membrane-proximal region of the erythropoietin receptor (EPOR) by a Stat5-dependent pathway
OBJECTIVE: Erythropoietin is essential for red blood cell development in vivo and is also an important therapeutic agent to treat anemia resulting from kidney failure or bone marrow suppression. The erythropoietin receptor (EPOR) elicits both positive and negative regulatory signaling pathways, prim...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2388246/ https://ncbi.nlm.nih.gov/pubmed/14662339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2003.08.009 |
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