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The canonical Wnt signaling antagonist DKK2 is an essential effector of PITX2 function during normal eye development

Local control of cell signaling activity and integration of inputs from multiple signaling pathways are central for normal development but the underlying mechanisms remain poorly understood. Here we show that Dkk2, encoding an antagonist of canonical Wnt signaling, is an essential downstream target...

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Detalhes bibliográficos
Main Authors: Gage, Philip J., Qian, Min, Wu, Dianqing, Rosenberg, Kevin I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2387126/
https://ncbi.nlm.nih.gov/pubmed/18367164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.02.030
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