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Protein-tyrosine Phosphatase 1B Expression Is Induced by Inflammation in Vivo

Protein-tyrosine phosphatase 1B (PTP1B) is a major negative regulator of insulin and leptin sensitivity. PTP1B overexpression in adipose tissue and skeletal muscle of humans and rodents may contribute to insulin resistance and obesity. The mechanisms mediating PTP1B overexpression in obese and diabe...

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Detalhes bibliográficos
Main Authors: Zabolotny, Janice M., Kim, Young-Bum, Welsh, Laura A., Kershaw, Erin E., Neel, Benjamin G., Kahn, Barbara B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386946/
https://ncbi.nlm.nih.gov/pubmed/18281274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800061200
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