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C-terminal Movement during Gating in Cyclic Nucleotide-modulated Channels

Activation of cyclic nucleotide-modulated channels such as CNG and HCN channels is promoted by ligand-induced conformational changes in their C-terminal regions. The primary intersubunit interface of these C termini includes two salt bridges per subunit, formed between three residues (one positively...

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Detalhes bibliográficos
Main Authors: Craven, Kimberley B., Olivier, Nelson B., Zagotta, William N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386932/
https://ncbi.nlm.nih.gov/pubmed/18367452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710463200
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