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Differential protein expression following low temperature culture of suspension CHO-K1 cells

BACKGROUND: To ensure maximal productivity of recombinant proteins (rP) during production culture it is typical to encourage an initial phase of rapid cell proliferation to achieve high biomass followed by a stationary phase where cellular energies are directed towards production of rP. During many...

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Autors principals: Kumar, Niraj, Gammell, Patrick, Meleady, Paula, Henry, Michael, Clynes, Martin
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386802/
https://ncbi.nlm.nih.gov/pubmed/18430238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-8-42
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