Mapping the molecular basis for growth related phenotypes in industrial producer CHO cell lines using differential proteomic analysis

BACKGROUND: The ability to achieve high peak viable cell density earlier in CHO cell culture and maintain an extended cell viability throughout the production process is highly desirable to increase recombinant protein yields, reduce host cell impurities for downstream processing and reduce the cost...

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Detalhes bibliográficos
Publicado no:BMC Biotechnol
Main Authors: Bryan, Laura, Henry, Michael, Kelly, Ronan M., Frye, Christopher C., Osborne, Matthew D., Clynes, Martin, Meleady, Paula
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305936/
https://ncbi.nlm.nih.gov/pubmed/34301236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-021-00704-8
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