Inhibition of Glycogen Synthase Kinase-3 in Androgen-Responsive Prostate Cancer Cell Lines: Are GSK Inhibitors Therapeutically Useful?

The glycogen synthase kinase 3 (GSK-3) is a serine/threonine kinase widely expressed in mammalian tissues. Initially identified by its ability to modulate glycogen synthesis, GSK-3 turned out to be a multifunctional enzyme, able to phosphorylate many proteins, including members of the steroid recept...

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Main Authors: Rinnab, Ludwig, Schütz, Stefanie V, Diesch, Jeannine, Schmid, Evi, Küfer, Rainer, Hautmann, Richard E, Spindler, Klaus-Dieter, Cronauer, Marcus V
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386547/
https://ncbi.nlm.nih.gov/pubmed/18516299
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