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A systems biology approach to analyse amplification in the JAK2-STAT5 signalling pathway

BACKGROUND: The amplification of signals, defined as an increase in the intensity of a signal through networks of intracellular reactions, is considered one of the essential properties in many cell signalling pathways. Despite of the apparent importance of signal amplification, there have been few a...

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Detalhes bibliográficos
Main Authors: Vera, Julio, Bachmann, Julie, Pfeifer, Andrea C, Becker, Verena, Hormiga, Jose A, Darias, Nestor V Torres, Timmer, Jens, Klingmüller, Ursula, Wolkenhauer, Olaf
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386439/
https://ncbi.nlm.nih.gov/pubmed/18439261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-2-38
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