A systems biology approach to analyse amplification in the JAK2-STAT5 signalling pathway

BACKGROUND: The amplification of signals, defined as an increase in the intensity of a signal through networks of intracellular reactions, is considered one of the essential properties in many cell signalling pathways. Despite of the apparent importance of signal amplification, there have been few a...

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Autori principali: Vera, Julio, Bachmann, Julie, Pfeifer, Andrea C, Becker, Verena, Hormiga, Jose A, Darias, Nestor V Torres, Timmer, Jens, Klingmüller, Ursula, Wolkenhauer, Olaf
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2008
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386439/
https://ncbi.nlm.nih.gov/pubmed/18439261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-2-38
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