A Constitutional Translocation t(1;17)(p36.2;q11.2) in a Neuroblastoma Patient Disrupts the Human NBPF1 and ACCN1 Genes

The human 1p36 region is deleted in many different types of tumors, and so it probably harbors one or more tumor suppressor genes. In a Belgian neuroblastoma patient, a constitutional balanced translocation t(1;17)(p36.2;q11.2) may have led to the development of the tumor by disrupting or activating...

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Auteurs principaux: Vandepoele, Karl, Andries, Vanessa, Van Roy, Nadine, Staes, Katrien, Vandesompele, Jo, Laureys, Geneviève, De Smet, Els, Berx, Geert, Speleman, Frank, van Roy, Frans
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2008
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386287/
https://ncbi.nlm.nih.gov/pubmed/18493581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002207
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