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A Constitutional Translocation t(1;17)(p36.2;q11.2) in a Neuroblastoma Patient Disrupts the Human NBPF1 and ACCN1 Genes

The human 1p36 region is deleted in many different types of tumors, and so it probably harbors one or more tumor suppressor genes. In a Belgian neuroblastoma patient, a constitutional balanced translocation t(1;17)(p36.2;q11.2) may have led to the development of the tumor by disrupting or activating...

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Detalhes bibliográficos
Main Authors: Vandepoele, Karl, Andries, Vanessa, Van Roy, Nadine, Staes, Katrien, Vandesompele, Jo, Laureys, Geneviève, De Smet, Els, Berx, Geert, Speleman, Frank, van Roy, Frans
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386287/
https://ncbi.nlm.nih.gov/pubmed/18493581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002207
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