NBPF1, a tumor suppressor candidate in neuroblastoma, exerts growth inhibitory effects by inducing a G1 cell cycle arrest

BACKGROUND: NBPF1 (Neuroblastoma Breakpoint Family, member 1) was originally identified in a neuroblastoma patient on the basis of its disruption by a chromosomal translocation t(1;17)(p36.2;q11.2). Considering this genetic defect and the frequent genomic alterations of the NBPF1 locus in several ca...

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Détails bibliographiques
Publié dans:BMC Cancer
Auteurs principaux: Andries, Vanessa, Vandepoele, Karl, Staes, Katrien, Berx, Geert, Bogaert, Pieter, Van Isterdael, Gert, Ginneberge, Daisy, Parthoens, Eef, Vandenbussche, Jonathan, Gevaert, Kris, van Roy, Frans
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440459/
https://ncbi.nlm.nih.gov/pubmed/25958384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1408-5
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