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Ku86 exists as both a full-length and a protease-sensitive natural variant in multiple myeloma cells

BACKGROUND: Truncated variants of Ku86 protein have previously been detected in 86% to 100% of freshly isolated patient multiple myeloma (MM) cells. Since, the Ku70/Ku86 heterodimer functions as the regulatory subunit of the DNA repair enzyme, DNA-dependent protein kinase, we have been interested in...

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Bibliografske podrobnosti
Main Authors:	Gullo, Charles A, Ge, Feng, Cow, Geraline, Teoh, Gerrard
Format:	Artigo
Jezik:	Inglês
Izdano:	BioMed Central 2008
Teme:	Primary Research
Online dostop:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2386117/ https://ncbi.nlm.nih.gov/pubmed/18442416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-8-4
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Ku86 exists as both a full-length and a protease-sensitive natural variant in multiple myeloma cells

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