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Efficient loading of HLA-DR with a T helper epitope by genetic exchange of CLIP

The HLA class II-associated invariant chain (Ii)-derived peptide (CLIP) occupies the peptide binding groove during assembly in the endoplasmic reticulum, travels with HLA class II to endosomal compartments, and is subsequently released to allow binding of antigenic peptides. We investigated whether...

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Bibliografiset tiedot
Päätekijät: van Bergen, Jeroen, Schoenberger, Stephen P., Verreck, Frank, Amons, Reinout, Offringa, Rienk, Koning, Frits
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The National Academy of Sciences of the USA 1997
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC23850/
https://ncbi.nlm.nih.gov/pubmed/9207120
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