A single amino acid substitution converts a carboxylesterase to an organophosphorus hydrolase and confers insecticide resistance on a blowfly

Resistance to organophosphorus (OP) insecticides is associated with decreased carboxylesterase activity in several insect species. It has been proposed that the resistance may be the result of a mutation in a carboxylesterase that simultaneously reduces its carboxylesterase activity and confers an O...

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Bibliographic Details
Main Authors: Newcomb, R. D., Campbell, P. M., Ollis, D. L., Cheah, E., Russell, R. J., Oakeshott, J. G.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences of the USA 1997
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC23844/
https://ncbi.nlm.nih.gov/pubmed/9207114
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