Induction of the IL-9 gene by HTLV-I Tax stimulates the spontaneous proliferation of primary adult T-cell leukemia cells by a paracrine mechanism

The etiologic agent of adult T-cell leukemia (ATL) is human T cell lymphotropic virus type I (HTLV-I). The HTLV-I protein Tax alters gene expression, including those of cytokines and their receptors, which plays an important role in early stages of ATL. Here we demonstrate that expression of interle...

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Detalhes bibliográficos
Main Authors: Chen, Jing, Petrus, Mike, Bryant, Bonita R., Phuc Nguyen, Vinh, Stamer, Mindy, Goldman, Carolyn K., Bamford, Richard, Morris, John C., Janik, John E., Waldmann, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2384140/
https://ncbi.nlm.nih.gov/pubmed/18339896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-113654
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