Ligand Specificity of Group I Biotin Protein Ligase of Mycobacterium tuberculosis

BACKGROUND: Fatty acids are indispensable constituents of mycolic acids that impart toughness & permeability barrier to the cell envelope of M. tuberculosis. Biotin is an essential co-factor for acetyl-CoA carboxylase (ACC) the enzyme involved in the synthesis of malonyl-CoA, a committed precurs...

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Hlavní autoři: Purushothaman, Sudha, Gupta, Garima, Srivastava, Richa, Ramu, Vasanthakumar Ganga, Surolia, Avadhesha
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2008
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2384007/
https://ncbi.nlm.nih.gov/pubmed/18509457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002320
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