Human Rhinovirus 1B Exposure Induces Phosphatidylinositol 3-Kinase–dependent Airway Inflammation in Mice

Rationale: Infection with rhinovirus (RV) triggers exacerbations of asthma and chronic obstructive lung disease. Objectives: We sought to develop a mouse model of RV employing RV1B, a minor group serotype that binds to the low-density lipoprotein receptor. Methods: C57BL/6 mice were inoculated intra...

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Detaylı Bibliyografya
Asıl Yazarlar: Newcomb, Dawn C., Sajjan, Umadevi S., Nagarkar, Deepti R., Wang, Qiong, Nanua, Suparna, Zhou, Ying, McHenry, Christina L., Hennrick, Kenneth T., Tsai, Wan C., Bentley, J. Kelley, Lukacs, Nicholas W., Johnston, Sebastian L., Hershenson, Marc B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Thoracic Society 2008
Konular:
D. Pulmonary Infections
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2383993/
https://ncbi.nlm.nih.gov/pubmed/18276942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200708-1243OC
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