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Multiple origins of resistance-conferring mutations in Plasmodium vivax dihydrofolate reductase

BACKGROUND: In order to maximize the useful therapeutic life of antimalarial drugs, it is crucial to understand the mechanisms by which parasites resistant to antimalarial drugs are selected and spread in natural populations. Recent work has demonstrated that pyrimethamine-resistance conferring muta...

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Bibliografski detalji
Glavni autori: Hawkins, Vivian N, Auliff, Alyson, Prajapati, Surendra Kumar, Rungsihirunrat, Kanchana, Hapuarachchi, Hapuarachchige C, Maestre, Amanda, O'Neil, Michael T, Cheng, Qin, Joshi, Hema, Na-Bangchang, Kesara, Sibley, Carol Hopkins
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2383903/
https://ncbi.nlm.nih.gov/pubmed/18442404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-7-72
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