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Transcriptional abnormality in myotonic dystrophy affects DMPK but not neighboring genes

Myotonic dystrophy (DM) is caused by the expansion of a trinucleotide repeat, CTG, in the 3′ untranslated region of a protein kinase gene, DMPK. We set out to determine what effect this expanded repeat has on RNA processing. The subcellular fractionation of RNA and the separate analysis of DMPK tran...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hamshere, Marion G., Newman, Emma E., Alwazzan, Madawi, Athwal, Balwinder S., Brook, J. David
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences of the USA 1997
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC23832/
https://ncbi.nlm.nih.gov/pubmed/9207102
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