Transcriptional abnormality in myotonic dystrophy affects DMPK but not neighboring genes
Myotonic dystrophy (DM) is caused by the expansion of a trinucleotide repeat, CTG, in the 3′ untranslated region of a protein kinase gene, DMPK. We set out to determine what effect this expanded repeat has on RNA processing. The subcellular fractionation of RNA and the separate analysis of DMPK tran...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23832/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9207102/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.14.7394 |
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