Expansion of a CUG trinucleotide repeat in the 3′ untranslated region of myotonic dystrophy protein kinase transcripts results in nuclear retention of transcripts

Expansion of a CTG trinucleotide repeat in the 3′ untranslated region (UTR) of DMPK, the gene encoding myotonic dystrophy protein kinase, induces the dominantly inherited neuromuscular disorder myotonic dystrophy (DM). Transcripts containing the expanded trinucleotide are abundant in differentiated...

Descripció completa

Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Davis, Brigid M., McCurrach, Mila E., Taneja, Krishan L., Singer, Robert H., Housman, David E.
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1997
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23831/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9207101/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.14.7388
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!