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Altered phosphorylation and intracellular distribution of a (CUG)(n) triplet repeat RNA-binding protein in patients with myotonic dystrophy and in myotonin protein kinase knockout mice
Myotonic dystrophy (DM) is associated with expansion of CTG repeats in the 3′-untranslated region of the myotonin protein kinase (DMPK) gene. The molecular mechanism whereby expansion of the (CUG)(n) repeats in the 3′-untranslated region of DMPK gene induces DM is unknown. We previously isolated a p...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences of the USA
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC24290/ https://ncbi.nlm.nih.gov/pubmed/9371827 |
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