Binding sites for the herpes simplex virus immediate-early protein ICP4 impose an increased dependence on viral DNA replication on simple model promoters located in the viral genome.

We examined the ability of binding sites for the herpes simplex virus immediate-early protein ICP4 to alter the regulation of closely linked promoters by placing strong ICP4 binding sites upstream or downstream of simple TATA promoters in the intact viral genome. We found that binding sites strongly...

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Detalles Bibliográficos
Main Authors: Koop, K E, Duncan, J, Smiley, J R
Formato: Artigo
Idioma:Inglês
Publicado: 1993
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC238188/
https://ncbi.nlm.nih.gov/pubmed/8230448
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