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N-Terminal Phosphorylation Sites of Herpes Simplex Virus 1 ICP0 Differentially Regulate Its Activities and Enhance Viral Replication

The herpes simplex virus 1 (HSV-1) infected cell protein 0 (ICP0) is an immediate-early phosphoprotein that transactivates viral gene expression. Evidence suggests that phosphorylation regulates the functions of ICP0, and three regions (termed regions I, II, and III) in the protein are known to be p...

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Détails bibliographiques
Auteurs principaux: Mostafa, Heba H., Thompson, Thornton W., Davido, David J.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571471/
https://ncbi.nlm.nih.gov/pubmed/23221554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02588-12
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