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Mutated primer binding sites interacting with different tRNAs allow efficient murine leukemia virus replication.

Two Akv murine leukemia virus-based retroviral vectors with primer binding sites matching tRNA(Gln-1) and tRNA(Lys-3) were constructed. The transduction efficiency of these mutated vectors was found to be comparable to that of a vector carrying the wild-type primer binding site matching tRNA(Pro). P...

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Autors principals: Lund, A H, Duch, M, Lovmand, J, Jørgensen, P, Pedersen, F S
Format: Artigo
Idioma:Inglês
Publicat: 1993
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC238174/
https://ncbi.nlm.nih.gov/pubmed/7693968
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