Mutated primer binding sites interacting with different tRNAs allow efficient murine leukemia virus replication.

Two Akv murine leukemia virus-based retroviral vectors with primer binding sites matching tRNA(Gln-1) and tRNA(Lys-3) were constructed. The transduction efficiency of these mutated vectors was found to be comparable to that of a vector carrying the wild-type primer binding site matching tRNA(Pro). P...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Lund, A H, Duch, M, Lovmand, J, Jørgensen, P, Pedersen, F S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238174/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7693968/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.12.7125-7130.1993
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