Mutated primer binding sites interacting with different tRNAs allow efficient murine leukemia virus replication.
Two Akv murine leukemia virus-based retroviral vectors with primer binding sites matching tRNA(Gln-1) and tRNA(Lys-3) were constructed. The transduction efficiency of these mutated vectors was found to be comparable to that of a vector carrying the wild-type primer binding site matching tRNA(Pro). P...
Guardat en:
| Publicat a: | J Virol |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1993
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238174/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7693968/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.12.7125-7130.1993 |
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