Viral determinants of simian immunodeficiency virus (SIV) virulence in rhesus macaques assessed by using attenuated and pathogenic molecular clones of SIVmac.

To identify viral determinants of simian immunodeficiency virus (SIV) virulence, two pairs of reciprocal recombinants constructed from a pathogenic (SIVmac239) and a nonpathogenic (SIVmac1A11) molecular clone of SIV were tested in rhesus macaques. A large 6.2-kb fragment containing gag, pol, env, an...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Marthas, M L, Ramos, R A, Lohman, B L, Van Rompay, K K, Unger, R E, Miller, C J, Banapour, B, Pedersen, N C, Luciw, P A
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1993
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238025/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8371353/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.10.6047-6055.1993
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