Viral determinants of simian immunodeficiency virus (SIV) virulence in rhesus macaques assessed by using attenuated and pathogenic molecular clones of SIVmac.

To identify viral determinants of simian immunodeficiency virus (SIV) virulence, two pairs of reciprocal recombinants constructed from a pathogenic (SIVmac239) and a nonpathogenic (SIVmac1A11) molecular clone of SIV were tested in rhesus macaques. A large 6.2-kb fragment containing gag, pol, env, an...

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Detalhes bibliográficos
Main Authors: Marthas, M L, Ramos, R A, Lohman, B L, Van Rompay, K K, Unger, R E, Miller, C J, Banapour, B, Pedersen, N C, Luciw, P A
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC238025/
https://ncbi.nlm.nih.gov/pubmed/8371353
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