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Viral determinants of simian immunodeficiency virus (SIV) virulence in rhesus macaques assessed by using attenuated and pathogenic molecular clones of SIVmac.

To identify viral determinants of simian immunodeficiency virus (SIV) virulence, two pairs of reciprocal recombinants constructed from a pathogenic (SIVmac239) and a nonpathogenic (SIVmac1A11) molecular clone of SIV were tested in rhesus macaques. A large 6.2-kb fragment containing gag, pol, env, an...

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Bibliografische gegevens
Gepubliceerd in:J Virol
Hoofdauteurs: Marthas, M L, Ramos, R A, Lohman, B L, Van Rompay, K K, Unger, R E, Miller, C J, Banapour, B, Pedersen, N C, Luciw, P A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 1993
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238025/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8371353/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.10.6047-6055.1993
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