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Viral determinants of simian immunodeficiency virus (SIV) virulence in rhesus macaques assessed by using attenuated and pathogenic molecular clones of SIVmac.

To identify viral determinants of simian immunodeficiency virus (SIV) virulence, two pairs of reciprocal recombinants constructed from a pathogenic (SIVmac239) and a nonpathogenic (SIVmac1A11) molecular clone of SIV were tested in rhesus macaques. A large 6.2-kb fragment containing gag, pol, env, an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Marthas, M L, Ramos, R A, Lohman, B L, Van Rompay, K K, Unger, R E, Miller, C J, Banapour, B, Pedersen, N C, Luciw, P A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1993
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC238025/
https://ncbi.nlm.nih.gov/pubmed/8371353
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