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Conformational changes affecting the V3 and CD4-binding domains of human immunodeficiency virus type 1 gp120 associated with env processing and with binding of ligands to these sites.

Two neutralizing human monoclonal antibodies (HuMAbs) directed against epitopes located near the tip of the V3 loop of human immunodeficiency virus type 1 env protein recognized solubilized gPr160, but not gp120, in radioimmunoprecipitation assays. Efficient immunoprecipitation of solubilized gp120...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: Pinter, A, Honnen, W J, Tilley, S A
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1993
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237978/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7688827/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.9.5692-5697.1993
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