A novel, glycan-dependent epitope in the V2 domain of human immunodeficiency virus type 1 gp120 is recognized by a highly potent, neutralizing chimpanzee monoclonal antibody.

An anti-gp120 monoclonal antibody (MAb), C108G (gamma 1, kappa), was isolated from a chimpanzee that had been infected with strain IIIB of human immunodeficiency virus type 1 (HIV-1IIIB) and subsequently immunized with the recombinant glycoprotein rgp160MN. This MAb is specific for the IIIB strain o...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Warrier, S V, Pinter, A, Honnen, W J, Girard, M, Muchmore, E, Tilley, S A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236391/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7515975/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.7.4636-4642.1994
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