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Evidence for a base-paired region of hepatitis B virus pregenome encapsidation signal which influences the patterns of precore mutations abolishing HBe protein expression.

In two natural HBe-minus hepatitis B virus mutants, expression of HBe protein was abrogated by a nonsense mutation at precore codon 28 and a frameshift mutation at codon 29, respectively. Both mutants contained an additional nucleotide substitution(s) which was found by transfection experiments to b...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Tong, S P, Li, J S, Vitvitski, L, Kay, A, Treépo, C
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1993
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237970/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8350418/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.9.5651-5655.1993
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