Hepatitis B virus genotype A rarely circulates as an HBe-minus mutant: possible contribution of a single nucleotide in the precore region.

The emergence of HBe-minus hepatitis B virus (HBV) mutants, usually through a UAG nonsense mutation at codon 28 of the precore region, helps the virus to survive the anti-HBe immune response of the host. Host and viral factors that predispose to the emergence of such mutants are not well characteriz...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Li, J S, Tong, S P, Wen, Y M, Vitvitski, L, Zhang, Q, Trépo, C
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1993
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237941/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8350403/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.9.5402-5410.1993
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