Pharmacological analysis of cyclooxygenase-1 in inflammation

The enzymes cyclooxygenase-1 and cyclooxygenase-2 (COX-1 and COX-2) catalyze the conversion of arachidonic acid to prostaglandin (PG) H(2), the precursor of PGs and thromboxane. These lipid mediators play important roles in inflammation and pain and in normal physiological functions. While there are...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Smith, Christopher J., Zhang, Yan, Koboldt, Carol M., Muhammad, Jerry, Zweifel, Ben S., Shaffer, Alex, Talley, John J., Masferrer, Jaime L., Seibert, Karen, Isakson, Peter C.
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1998
Fag:	Biological Sciences
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23795/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9789085/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.22.13313
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