Pharmacological analysis of cyclooxygenase-1 in inflammation

The enzymes cyclooxygenase-1 and cyclooxygenase-2 (COX-1 and COX-2) catalyze the conversion of arachidonic acid to prostaglandin (PG) H(2), the precursor of PGs and thromboxane. These lipid mediators play important roles in inflammation and pain and in normal physiological functions. While there are...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Smith, Christopher J., Zhang, Yan, Koboldt, Carol M., Muhammad, Jerry, Zweifel, Ben S., Shaffer, Alex, Talley, John J., Masferrer, Jaime L., Seibert, Karen, Isakson, Peter C.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23795/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9789085/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.22.13313
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