Large E1B proteins of adenovirus types 5 and 12 have different effects on p53 and distinct roles in cell transformation.

The formation of complexes between oncoproteins of DNA tumor viruses and the cellular protein p53 is thought to result in inactivation of the growth suppressor function of p53. In cells transformed by nononcogenic human adenovirus type 5 (Ad5), the 55-kDa protein encoded by E1B forms a stable comple...

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Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	van den Heuvel, S J, van Laar, T, The, I, van der Eb, A J
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1993
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237920/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8350396/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.9.5226-5234.1993
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