Large E1B proteins of adenovirus types 5 and 12 have different effects on p53 and distinct roles in cell transformation.

The formation of complexes between oncoproteins of DNA tumor viruses and the cellular protein p53 is thought to result in inactivation of the growth suppressor function of p53. In cells transformed by nononcogenic human adenovirus type 5 (Ad5), the 55-kDa protein encoded by E1B forms a stable comple...

Disgrifiad llawn

Manylion Llyfryddiaeth

Cyhoeddwyd yn:	J Virol
Prif Awduron:	van den Heuvel, S J, van Laar, T, The, I, van der Eb, A J
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	American Society for Microbiology (ASM) 1993
Pynciau:	Research Article
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237920/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8350396/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.9.5226-5234.1993
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