Large E1B proteins of adenovirus types 5 and 12 have different effects on p53 and distinct roles in cell transformation.

The formation of complexes between oncoproteins of DNA tumor viruses and the cellular protein p53 is thought to result in inactivation of the growth suppressor function of p53. In cells transformed by nononcogenic human adenovirus type 5 (Ad5), the 55-kDa protein encoded by E1B forms a stable comple...

詳細記述

書誌詳細

出版年:	J Virol
主要な著者:	van den Heuvel, S J, van Laar, T, The, I, van der Eb, A J
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 1993
主題:	Research Article
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237920/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8350396/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.9.5226-5234.1993
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