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Multiple loop structures critical for ligand binding of the integrin α4 subunit in the upper face of the β-propeller mode 1

A non-I-domain integrin, α4β1, recognizes vascular cell adhesion molecule 1 (VCAM-1) and the IIICS portion of fibronectin. To localize regions of α4 critical for ligand binding, we swapped several predicted loops within or near the putative ligand-binding site of α4 (which spans repeats 2–5 of the s...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Irie, Atsushi, Kamata, Tetsuji, Takada, Yoshikazu
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The National Academy of Sciences of the USA 1997
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC23791/
https://ncbi.nlm.nih.gov/pubmed/9207068
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