Nef from primary isolates of human immunodeficiency virus type 1 suppresses surface CD4 expression in human and mouse T cells.

The human immunodeficiency virus type 1 (HIV-1) nef gene was originally described as a negative regulator of transcription from the viral long terminal repeat promoter. This observation has been disputed, and the function of Nef remains unclear. In vivo experiments have indicated that an intact nef...

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Vydáno v:	J Virol
Hlavní autoři:	Anderson, S, Shugars, D C, Swanstrom, R, Garcia, J V
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1993
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237880/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8331733/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.8.4923-4931.1993
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